The typical symptoms of Retinitis Pigmentosa are the difficulty of adapting to darkness. Can arrive at a true form of night blindness the progressive narrowing of the visual field. In advanced stages of the disease remaining only a small area of central vision and visual field is called "tubular" or telescope reducing central vision. Often occurs only in advanced stages of the disease. It is not unusual to find patients for 60 years who can read a newspaper but are no longer able to navigate in unknown environments.

The diagnosis is based on symptoms and some diagnostic tests. the electroretinogram (ERG). Indicates the level of functioning of photoreceptors and can also pose diagnosis before symptoms appear.

- examination of the visual field: indicates which area of the vision is impaired and what are the areas that are not seen while keeping their gaze fixed ahead of him.
- examination of the fundus: shows the changes of the retina due to degenerative phenomena that affect. Useful angiographic examinations (FAG and ICGA), the examination dell'autofluorescenza el'OCT (optical coherence tomography to) a sort of TAC of the retina that provides images of sections of the retina.

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